Critical Assessment
of Techniques for
Protein Structure PredictioN

The CASP is experiment/competition between protein structure prediction groups to accurately model the 3D structures of proteins. The CASPs have been running on biannual basis for last 10 years. We are currently in preparation for CASP-6 which will take place in the summer of 2004. (Please visit Prediction Center and CASP discussion forums Forcasp website for updates and target announcements. You might want to sign up for mailling list as well)

The aim of the CASP experiment is at establishing the current state of the art in protein structure prediction, identifying what progress has been made, and highlighting where future effort may be most productively focused. The broad goals of the CASP experiment are to address the following questions about the current state of the art in protein structure prediction:

  1. Are the models produced similar to the corresponding experimental structure?
  2. Is the mapping of the target sequence onto the proposed structure (i.e. the alignment) correct?
  3. Have similar structures that a model can be based on been identified?
  4. Are the details of the models correct?
  5. Has there been progress from the earlier CASPs?
  6. What methods are most effective?
  7. Where can future effort be most productively focused?

    Protein Structure Prediction Center

    The Prediction Center has been organized to to provide support for CASP data collection and evaluation. All data from current and past experiments can be found at Download Area"

    Historic CASP Data

    CASP2 Local Mirror
    CASP2 Evaluation Criteria
    CASP1 Model Database -
 
Question or Comments / Contact Us